You are viewing the site in preview mode

Skip to main content

Table 3 Independent determinants of EF, DT, E/e’ in the anthracycline plus taxane group based on Model 2

From: Effects of taxane-anthracycline and taxane only treatment on cardiac function in breast cancer—a retrospective cohort study

 

Effect size (95% CI)

p

EF (%)

Age (year)

-0.1 (-0.2;0)

0.006

Hypertension

-2.8 (-4.8;-0.8)

0.006

DT (msec)

-

-

-

E/e’

Age (year)

1 (1;1)

< 0.001

BMI (kg/m2)

1 (1;1)

0.044

Hypertension

0.8 (0.7;0.9)

0.002

Diabetes

0.8 (0.7;1)

0.021

  1. Results based on linear mixed models. p < 0.05 was considered statistically significant. 95% CI, 95% confidence interval; EF, ejection fraction; DT, deceleration time; E/ e’, ratio of early diastolic flow peak velocity of the mitral valve (E) and early diastolic peak velocity of mitral valve annulus (e’). Model 2 was adjusted for age, body mass index, hypertension, diabetes mellitus, hyperlipidaemia, current smoking, major adverse cardiac events, previous chemotherapy as fixed effects