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Table 1 Clinical characteristics of patients with and without a history of cancer according to myocardial injury status

From: Cancer and myocardial injury in patients with suspected acute coronary syndrome

  

Without cancer

With cancer

 
 

Total

Without MI

With MI

Without MI

With MI

p

 

3626

2319

923

256

128

 

Age, years

68[55–79]

65 [51–76]a

74 [60–83]b

75 [65–80]b

80 [72–85]c

0.001

Male sex

2072 (57.1)

1261 (54.4)a

563 (61.0)b

161 (62.9)a,b

87 (68.0)b

0.001

Female sex

1554 (42.9)

1058 (45.6)a

360 (39.0)b

95 (37.1)a,b

41 (32.0)b

0.001

Risk factors and comorbidities

 Hypertension

2195 (60.6)

1247 (53.8)a

672 (72.8)b

175 (68.4)b

101 (78.9)b

0.001

 Smoker

1216 (33.5)

701 (30.2)a

380 (41.2)b

87 (34.0)a,b

48 (37.5)a,b

0.001

 Diabetes

925(25.5)

466 (20.1)a

288 (31.2)b

60 (23.4)a,b

38 (29.7)a,b

0.001

 Prior myocardial infarction

719 (19.8)

392 (16.9)a

242 (26.2)b

45 (17.6)a

40 (31.3)b

0.001

 Congestive heart failure

257 (7.1)

109 (4.7)a

117 (12.7)b

14 (5.5)a

17 (13.3)b

0.001

 Stroke

284 (7.8)

124 (5.3)a

113 (12.2)b

27 (10.5)b

20 (15.6)b

0.001

 Kidney disease

296 (8.2)

84 (3.6)a

159 (17.2)b

20 (7.8)c

33 (25.8)b

0.001

 COPD

651 (18.0)

367 (15.8)a

199 (21.6)b

51 (19.9)a,b

34 (26.6)b

0.001

Symptoms

 Chest pain

1894 (52.2)

1255 (54.1)a

458 (49.6)a

122 (47.7)a

59 (46.1)a

0,02

 Dyspnea

606 (16.7)

284 (12.2)a

238 (25.8)b

41 (16.0)a

43 (33.6)b

0.001

 Syncope

245 (6.8)

162 (7.0)a

56 (6.1)a

20 (7.8)a

7 (5.5)a

0.001

 Other symptoms

1205 (33.2)

830 (35.8)a

248 (26.9)b

96 (37.5)a,c

31 (24.2)a,b

0.001

Exploration

 Heart rate (bmp)

79[67–95]

77 [66–90]a

83 [68–105]b

76 [65–93]a

87 [70–108]b

0.001

 Systolic blood pressure (mmHg)

138[121–155]

138 [123–153]a

137 [120–159]a

138 [120–156]a

134 [115–154]a

0.191

 Oxygen saturation (%)

98 [96–100]

99 [97–100]a

97 [94–99]b

98 [96–100]a

97 [91–98]c

0.001

Electrocardiogram

 Atrial fibrillation

574 (16.7)

281 (12.8)a

218 (24.7)b

41 (17.7)a,b

34 (27.4)b

0.005

 RBBB or LBBB

529 (15.4)

270 (12.3)a

190 (21.5)b,c

35 (15.1)a,c

34 (27.4)b

0.004

 Pacemaker stimulation

76 (2.2)

36 (1.6)a

27 (3.1)a

3 (1.3)a

10 (8.1)b

0.006

Blood test

 Glucose (mg/dl)

111[95–147]

106 [93–131]a

133 [104–187]b

114 [98–140]a

128 [100–174]b

0.001

 Glomerular filtration rate (ml/min/m2)

81[60–100]

85 [69–105]a

65 [45–90]b

78 [59–93]c

53 [36–74]d

0.001

 Hemoglobin (g/dl)

13.4[12.1–14.7]

13.6 [12.4–14.9]a

13.2 [11.6–14.6]b

13.3 [11.7–14.4]b

12 [10.8–13.3]c

0.001

  1. Each superscript letter indicates a subset of the 4 groups analyzed for which the means or proportions showed no difference at a significance level of 0.05
  2. MI Myocardial injury, COPD Chronic obstructive pulmonary disease, LBBB Left bundle branch block, RBBB Right bundle branch block