Fig. 5
From: Acute vascular and cardiac effects of lenvatinib in mice

Echocardiography in lenvatinib-treated mice on day 2 (cohort 1 & 2) and 7 (cohort 2). Lenvatinib caused a reversible reduction in LVEF. A LVEF of mice from cohort 1 was measured on day 2. B LVEF in mice from cohort 2 on both examination days. LVEF = left ventricular ejection fraction. Data is represented as mean ± SEM. N = 8 per cohort. A Mann–Whitney test (B) Two-way ANOVA (***p < 0.001, ****p < 0.0001)