Table 1 TAVR in cancer survivors with prior chest radiation - key considerations

Cancer survivor with prior C-XRT

 • Radiation causes fibrosis and valve calcification, leading to aortic stenosis.

Severe aortic stenosis

 • Very high mortality within 2 years if untreated.

 • SAVR is often risky due to radiation-induced fibrosis.

TAVR as an alternative

 • A less invasive treatment, ideal for high-risk patients.

Expected outcomes

 • Short-term survival at 30 days is comparable to non-C-XRT patients.

 • Long-term risks include a higher likelihood of heart failure and increased 1-year mortality.

Management plan

 • Early intervention, close monitoring, and collaborative care with oncologists are essential.