Fig. 2
From: Increasing clinicians’ suspicion of ATTR amyloidosis using a retrospective algorithm

PYP Change Point Analysis. Change point analysis of PYP orders over time. The cumulative PYP orders (blue line) significantly increased after March 15th, 2021 (green line). Regression coefficient (orange line) before change point was 1.27 (95% CI 1.25–1.40) vs. after 6.31 (95% CI 6.11–6.52) (p < 0.001). Knowing that the new protocol was initiated on April 4th, 2021, the results suggest that the new protocol resulted in increased PYP orders